The Napa River is a river approximately 55 miles (89 km) long in the U.S. state of California. It drains a famous wine-growing region called the Napa Valley, in the mountains north of the San Francisco Bay. Milliken Creek and Mt. Veeder watersheds are a few of its many tributaries. The river mouth is at Vallejo, where the intertidal zone of fresh and salt waters flow into the Carquinez Strait and the San Pablo Bay.